NAHRly normalizes read depth in a given genomic region across multiple samples and then uses the troughs of the histogram of normalized read depths to threshold them, thereby clustering the samples into copy-number classes. (This approach is borrowed from the field of image segmentation .)
Using the labels assigned to samples by the histogram-based method outlined above, Naive Bayes was used to compute
This dashboard visualizes the Naive-Bayes confidence of inferred copy numbers and compares the histogram-based and Naive-Bayes-based predicted copy numbers.
{{ bayes_inferred_copy_number }} | |
{{ histogram_inferred_copy_number }} | {{ number_samples(histogram_inferred_copy_number, bayes_inferred_copy_number) }} |